In Vivo Imaging of Amyloid Deposition in Alzheimer Disease Using the Radioligand <sup>18</sup>F-AV-45 (Flobetapir F 18)

2010672 citationsJournal Articlebronze Open Access

Authors

Dean F. Wong · Johns Hopkins University

Paul B. Rosenberg · Johns Hopkins University

Yun Zhou · Johns Hopkins University

Anil Kumar · Johns Hopkins University

Vanessa Raymont · Johns Hopkins University

Hayden T. Ravert · Johns Hopkins University

Robert F. Dannals ·

Abstract

(18)F-AV-45 was well tolerated, and PET showed significant discrimination between AD patients and HCs, using either a parametric reference region method (DVR) or a simplified SUVR calculated from 10 min of scanning 50-60 min after (18)F-AV-45 administration.

Topics & Keywords

Alzheimer's disease research and treatments Dementia and Cognitive Impairment Research Medical Imaging Techniques and Applications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Nuclear Medicine

Volume 51, Issue 6, pp. 913-920

DOI: 10.2967/jnumed.109.069088

Field-Weighted Citation Impact: 31.44