Type 2 Diabetes Mellitus Coincident with Pulmonary Tuberculosis Is Associated with Heightened Systemic Type 1, Type 17, and Other Proinflammatory Cytokines

2013117 citationsJournal Articlegreen Open Access

Authors

Nathella Pavan Kumar · National Institute of Research in Tuberculosis

Rathinam Sridhar · Stanley Medical College

Vaithilingam V. Banurekha · National Institute of Research in Tuberculosis

M S Jawahar · National Institute of Research in Tuberculosis

Michael P. Fay · Cancer Research And Biostatistics

Thomas B. Nutman · National Institutes of Health

Subash Babu

Abstract

Our data reveal that tuberculosis with diabetes is characterized by heightened cytokine responsiveness, indicating that chronic inflammation underlying type 2 diabetes potentially contributes to increased immune pathology and poor control in tuberculosis infection.

Topics & Keywords

Tuberculosis Research and Epidemiology Pneumocystis jirovecii pneumonia detection and treatment Mycobacterium research and diagnosis

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Annals of the American Thoracic Society

Volume 10, Issue 5, pp. 441-449

DOI: 10.1513/annalsats.201305-112oc

Field-Weighted Citation Impact: 3.74