Connecting mTORC1 signaling to SREBP-1 activation

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Abstract

The discovery of a connection between mTORC1 and SREBP-1 opens a new chapter in our understanding of the molecular mechanisms regulating de-novo lipogenesis. A better comprehension of these mechanisms is key for the development of new tools to treat NAFLD and its complications.

Topics & Keywords

Cholesterol and Lipid Metabolism PI3K/AKT/mTOR signaling in cancer Lipid metabolism and biosynthesis

Publication Details

Published in: Current Opinion in Lipidology

Volume 23, Issue 3, pp. 226-234

DOI: 10.1097/mol.0b013e328352dd03

Field-Weighted Citation Impact: 22.03

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Connecting mTORC1 signaling to SREBP-1 activation

Authors

Abstract

Topics & Keywords

Publication Details