Metformin for the Treatment of Hyperandrogenism in Adolescents with Type 1 Diabetes Mellitus

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Authors

Ethel Codner · University of Chile

Germán Íñiguez · University of Chile

Patricia López · University of Chile

Verónica Mujica · Hospital Regional de Talca

Francisca Eyzaguirre · University of Chile

Sylvia Asenjo · University of Concepción

I Torrealba ·

Abstract

Treating hyperandrogenic T1D adolescents with metformin significantly decreased the serum androgens compared to the placebo, but metformin therapy did not significantly affect clinical parameters, such as hirsutism, ovulation and metabolic control.

Topics & Keywords

Ovarian function and disorders Reproductive Biology and Fertility Growth Hormone and Insulin-like Growth Factors

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Hormone Research in Paediatrics

Volume 80, Issue 5, pp. 343-349

DOI: 10.1159/000355513

Field-Weighted Citation Impact: 3.86