Genomic organization of human histo-blood group ABO genes

1995217 citationsJournal Article

Authors

Patricia D. McNeill · University of Washington

Sen‐itiroh Hakomori · University of Washington

Abstract

We have isolated human genomic DNA clones encompassing 30 kbp of the histo-blood group ABO locus. The locations of the exons have been mapped and the nucleotide sequences of the exon-intron boundaries have been determined. The human ABO genes consist of at least seven exons, and the coding sequence in the seven coding exons spans over 18 kb of the genomic DNA. The exons range in size from 28 to 688 bp, with most of the coding sequence lying in exon 7.

Topics & Keywords

Blood groups and transfusion Cancer-related molecular mechanisms research Cytomegalovirus and herpesvirus research

Publication Details

Published in: Glycobiology

Volume 5, Issue 1, pp. 51-58

DOI: 10.1093/glycob/5.1.51

Field-Weighted Citation Impact: 4.58

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Genomic organization of human histo-blood group ABO genes

Authors

Abstract

Topics & Keywords

Publication Details