The Future of Genetic Studies of Complex Human Diseases

19965,374 citationsJournal Article

Authors

Kathleen R. Merikangas · Yale University

Abstract

The identification of the genetic basis of complex human diseases such as schizophrenia and diabetes has proven difficult. In their Perspective, Risch and Merikangas propose that we can best accomplish this goal by combining the power of the human genome project with association studies, a method for determining the basis of a genetic disease.

Topics & Keywords

Genetic Associations and Epidemiology Genomics and Rare Diseases BRCA gene mutations in cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Science

Volume 273, Issue 5281, pp. 1516-1517

DOI: 10.1126/science.273.5281.1516

Field-Weighted Citation Impact: 96.71