First‐trimester screening for trisomy 21 by free beta‐human chorionic gonadotropin and pregnancy‐associated plasma protein‐A: impact of maternal and pregnancy characteristics

2008287 citationsJournal Articlebronze Open Access

Authors

Karl Oliver Kagan · Harris Birthright Research Centre for Fetal Medicine

Francisca S. Molina · King's College Hospital

K. H. Nicolaides · King's College Hospital

Abstract

In first-trimester biochemical screening for trisomy 21 it is essential to adjust the measured values of free beta-hCG and PAPP-A for maternal and pregnancy characteristics.

Topics & Keywords

Prenatal Screening and Diagnostics Parvovirus B19 Infection Studies Fetal and Pediatric Neurological Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Ultrasound in Obstetrics and Gynecology

Volume 31, Issue 5, pp. 493-502

DOI: 10.1002/uog.5332

Field-Weighted Citation Impact: 40.25