Incidence and Prognosis of Synchronous and Metachronous Bilateral Breast Cancer

2007217 citationsJournal Articlebronze Open Access

Authors

Mikael Hartman · Sophiahemmet Hospital

Kamila Czene · Karolinska Institutet

Marie Reilly · Sophiahemmet Hospital

Jan Adolfsson · Karolinska Institutet

Jonas Bergh · Karolinska University Hospital

Hans‐Olov Adami · Sophiahemmet Hospital

Paul W. Dickman ·

Abstract

We found profound differences in the incidence trends and prognostic outlook between synchronous and metachronous bilateral breast cancer diagnosed at different ages. Adjuvant chemotherapy therapy has a dual effect on metachronous cancer: it reduces the risk, while at the same time it seems to worsen the prognosis.

Topics & Keywords

Breast Cancer Treatment Studies Breast Lesions and Carcinomas Global Cancer Incidence and Screening

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 25, Issue 27, pp. 4210-4216

DOI: 10.1200/jco.2006.10.5056

Field-Weighted Citation Impact: 2.64