Myocardial Reperfusion Injury

20073,657 citationsReview

Authors

Derek M. Yellon · University College Hospital

Abstract

Lethal reperfusion injury is a paradoxical type of myocardial injury caused by the restoration of coronary blood flow after an ischemic episode. This review focuses on the mechanisms of the injury, on attempts to protect the heart against it, and on promising new approaches to cardioprotection during percutaneous coronary intervention.

Topics & Keywords

Cardiac Ischemia and Reperfusion Cardiac Arrest and Resuscitation Cardiac electrophysiology and arrhythmias

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 357, Issue 11, pp. 1121-1135

DOI: 10.1056/nejmra071667

Field-Weighted Citation Impact: 72.00