Enhanced ZAG production by subcutaneous adipose tissue is linked to weight loss in gastrointestinal cancer patients

2011125 citationsJournal Articlehybrid Open Access

Authors

Tomáš Mráček · University of Liverpool

Nathan Stephens · University of Edinburgh

Dan Gao · University of Liverpool

Yi Bao · University of Liverpool

J. A. Ross · University of Edinburgh

Mikael Rydén · Karolinska University Hospital

Peter Arner ·

Abstract

Zinc-α2-glycoprotein expression and secretion by adipose tissue is enhanced in cachectic cancer patients. Given its lipid-mobilising effect, ZAG may contribute to adipose atrophy associated with cancer cachexia in human beings.

Topics & Keywords

Nutrition and Health in Aging Body Composition Measurement Techniques Adipokines, Inflammation, and Metabolic Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: British Journal of Cancer

Volume 104, Issue 3, pp. 441-447

DOI: 10.1038/sj.bjc.6606083

Field-Weighted Citation Impact: 6.94