Resveratrol Oligomers from <i>Vatica albiramis</i>

201053 citationsJournal Article

Authors

Naohito Abe · Gifu Pharmaceutical University

Tetsuro Ito · Tokai Gakuin University

Kenji Ohguchi · Gifu Pharmaceutical University

Minori Nasu · Tokai Gakuin University

Yuichi Masuda · Tokai Gakuin University

Masayoshi Oyama · Tokai Gakuin University

Yoshinori Nozawa ·

Abstract

Five new stilbenoids, vatalbinosides A-E (1-5), and 13 known compounds (6-18) were isolated from the stem of Vatica albiramis. The effects of these new compounds on interleukin-1β-induced production of matrix metalloproteinase-1 (MMP-1) in human dermal fibroblasts were examined. Three resveratrol tetramers, (-)-hopeaphenol (6), vaticanol C (13), and stenophyllol C (14), were identified as strong inhibitors of MMP-1 production.

Topics & Keywords

Sirtuins and Resveratrol in Medicine Bioactive natural compounds Antimicrobial Peptides and Activities

Publication Details

Published in: Journal of Natural Products

Volume 73, Issue 9, pp. 1499-1506

DOI: 10.1021/np1002675

Field-Weighted Citation Impact: 2.33

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Resveratrol Oligomers from <i>Vatica albiramis</i>

Authors

Abstract

Topics & Keywords

Publication Details