Renoprotective Effect of the Angiotensin-Receptor Antagonist Irbesartan in Patients with Nephropathy Due to Type 2 Diabetes

20015,972 citationsJournal Articlebronze Open Access

Authors

Edmund J. Lewis · Rush University Medical Center

Lawrence G. Hunsicker · University of Iowa

William R. Clarke · University of Iowa

Tomás Berl · University of Colorado Denver

Marc A. Pohl · Cleveland Clinic

Julia B. Lewis · Vanderbilt University

Eberhard Ritz

Abstract

The angiotensin-II-receptor blocker irbesartan is effective in protecting against the progression of nephropathy due to type 2 diabetes. This protection is independent of the reduction in blood pressure it causes.

Topics & Keywords

Blood Pressure and Hypertension Studies Renin-Angiotensin System Studies Hormonal Regulation and Hypertension

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 345, Issue 12, pp. 851-860

DOI: 10.1056/nejmoa011303

Field-Weighted Citation Impact: 210.12