SUBRETINAL DRUSENOID DEPOSITS IN NON-NEOVASCULAR AGE-RELATED MACULAR DEGENERATION

2012368 citationsJournal Articlegreen Open Access

Authors

Christine A. Curcio · Ophthalmology Associates (United States)

Jeffrey D. Messinger · Ophthalmology Associates (United States)

Kenneth R. Sloan

Gerald McGwin · University of Alabama at Birmingham

Nancy E. Medeiros · Retina Specialists

Richard F. Spaide · Vitreous Retina Macula Consultants of New York

Abstract

Subretinal drusenoid deposits and BlinD prevalence in age-related macular degeneration eyes are high. Subretinal drusenoid deposits organized morphology, topography, and impact on surrounding photoreceptors imply specific processes of biogenesis. Contrasting topographies of subretinal drusenoid deposits and BlinD suggest relationships with differentiable aspects of rod and cone physiology, respectively. A 2-lesion 2-compartment biogenesis model incorporating outer retinal lipid homeostasis is presented.

Topics & Keywords

Retinal Diseases and Treatments Retinal Imaging and Analysis Retinal Development and Disorders

Publication Details

Published in: Retina

Volume 33, Issue 2, pp. 265-276

DOI: 10.1097/iae.0b013e31827e25e0

Field-Weighted Citation Impact: 21.38

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SUBRETINAL DRUSENOID DEPOSITS IN NON-NEOVASCULAR AGE-RELATED MACULAR DEGENERATION

Authors

Abstract

Topics & Keywords

Publication Details