Comparative effectiveness of nafcillin or cefazolin versus vancomycin in methicillin-susceptible Staphylococcus aureus bacteremia

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Authors

Marin L. Schweizer · University of Maryland, Baltimore

Jon P. Furuno · University of Maryland, Baltimore

Anthony D. Harris · University of Maryland, Baltimore

J. Kristie Johnson · University of Maryland, Baltimore

Michelle Shardell · University of Maryland, Baltimore

Jessina C. McGregor · Oregon Health & Science University

Kerri A. Thom

Abstract

Receipt of nafcillin or cefazolin was protective against mortality compared to vancomycin even when therapy was altered after culture results identified MSSA. Convenience of vancomycin dosing may not outweigh the potential benefits of nafcillin or cefazolin in the treatment of MSSA bacteremia.

Topics & Keywords

Antimicrobial Resistance in Staphylococcus Bacterial Identification and Susceptibility Testing Infective Endocarditis Diagnosis and Management

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Infectious Diseases

Volume 11, Issue 1, pp. 279-279

DOI: 10.1186/1471-2334-11-279

Field-Weighted Citation Impact: 7.08