Structural and functional aspects of the blood-brain barrier

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Authors

Milton Brightman · National Institutes of Health

Abstract

All organisms with a complex nervous system have a well-developed blood-central nervous system barrier. In the vertebrates the central nervous system (CNS) lies behind the protective blood-brain barrier (BBB) and blood-cerebrospinal fluid barrier (BCSFB). In all mammals the BBB is formed at the level of the cerebral capillary endothelial cells and the BCSFB by the choroid plexus epithelium.

Topics & Keywords

Drug Transport and Resistance Mechanisms Barrier Structure and Function Studies Diet and metabolism studies

Publication Details

Published in: Birkhäuser Basel eBooks

Volume 61, pp. 39-78

DOI: 10.1007/978-3-0348-8049-7_2

Field-Weighted Citation Impact: 27.60

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Structural and functional aspects of the blood-brain barrier

Authors

Abstract

Topics & Keywords

Publication Details