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The value of position-specific priors in motif discovery using MEME

2010112 citationsJournal Articlegold Open Access

Authors

Timothy L. Bailey · University of Queensland

Mikael Bodén · University of Queensland

Tom Whitington · University of Queensland

Philip Machanick · University of Queensland

Abstract

We conclude that using position-specific priors can substantially increase the power of EM-based motif discovery algorithms such as MEME algorithm.

Topics & Keywords

Genomics and Chromatin Dynamics Gene expression and cancer classification RNA Research and Splicing

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: BMC Bioinformatics

Volume 11, Issue 1, pp. 179-179

DOI: 10.1186/1471-2105-11-179

Field-Weighted Citation Impact: 6.08

The value of position-specific priors in motif discovery using MEME | Researchclopedia