Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

2013156 citationsJournal Articlehybrid Open Access

Authors

Sean P. Saunders · National Children’s Research Centre

Christabelle S.M. Goh · International Centre for Genetic Engineering and Biotechnology

Sara Brown · International Centre for Genetic Engineering and Biotechnology

Colin N.A. Palmer · University of Dundee

Rebecca M. Porter · University of Dundee

Christian Cole · International Centre for Genetic Engineering and Biotechnology

Linda Campbell

Abstract

In mice mutations in Matt cause a defective skin barrier and spontaneous dermatitis and atopy. A common SNP in MATT has an association with AD in human subjects.

Topics & Keywords

Dermatology and Skin Diseases Allergic Rhinitis and Sensitization Food Allergy and Anaphylaxis Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Allergy and Clinical Immunology

Volume 132, Issue 5, pp. 1121-1129

DOI: 10.1016/j.jaci.2013.08.046

Field-Weighted Citation Impact: 15.19