Adjuvant surgical therapy for patients with initially‐unresectable pancreatic cancer with long‐term favorable responses to chemotherapy

Surgical intervention should be considered for patients with initially-unresectable pancreatic cancers who demonstrate long-term favorable responses to chemotherapy. R0 resection may significantly contribute to cure, especially in patients with initially locally-advanced disease. Large cohort prospective studies will be necessary to demonstrate the efficacy of this strategy.