Myeloma bone disease: pathogenesis, current treatments and future targets

201467 citationsReviewbronze Open Access

Authors

Michelle A. Lawson · Sheffield Teaching Hospitals NHS Foundation Trust

John A. Snowden · Sheffield Teaching Hospitals NHS Foundation Trust

Andrew Chantry · Sheffield Teaching Hospitals NHS Foundation Trust

Abstract

Further research effectively targeting the mediators of MBD, targeting both bone resorption and bone formation, is urgently needed. This should translate promptly to clinical trials of combination therapy comprising anti-resorptives and bone anabolic therapies to demonstrate efficacy and improved outcomes over BPs.

Topics & Keywords

Multiple Myeloma Research and Treatments Bone health and treatments Myeloproliferative Neoplasms: Diagnosis and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: British Medical Bulletin

Volume 111, Issue 1, pp. 117-138

DOI: 10.1093/bmb/ldu016

Field-Weighted Citation Impact: 4.95