Role of circulating cytokines and chemokines in exertional heatstroke

2004121 citationsJournal Article

Authors

Kuo‐Cheng Lu · National Defense Medical Center

Jia‐Yi Wang · National Defense Medical Center

Shih‐Hua Lin · Restaurant Opportunities Centers United

Pauling Chu · National Defense Medical Center

Yuh‐Feng Lin · Restaurant Opportunities Centers United

Abstract

Proinflammatory cytokines IL-1beta, tumor necrosis factor alpha, IL-6; T helper 1 cytokines INF-gamma and IL-2 receptor; and chemokines IL-8, monocyte chemoattractant protein 1, and RANTES are increased in patients with exertional heatstroke. T helper 2 cytokines may play a role as anti-inflammatory cytokines. IL-6, interferon gamma, IL-2 receptor, and monocyte chemoattractant protein 1 may serve as prognostic indicators of disease severity in exertional heatstroke.

Topics & Keywords

Exercise and Physiological Responses Thermoregulation and physiological responses Adipose Tissue and Metabolism

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Critical Care Medicine

Volume 32, Issue 2, pp. 399-403

DOI: 10.1097/01.ccm.0000108884.74110.d9

Field-Weighted Citation Impact: 7.51