Topiramate as an Inhibitor of Carbonic Anhydrase Isoenzymes

2000317 citationsJournal Article

Authors

Abstract

These results indicate that TPM is more potent as an inhibitor of CA II and CA IV than of CA I, CA III, and CA VI. In all three species, AZM was usually 10 to 100 times more potent than TPM as an inhibitor of CA isozymes.

Topics & Keywords

Enzyme function and inhibition Ion channel regulation and function Cholinesterase and Neurodegenerative Diseases

Publication Details

Published in: Epilepsia

Volume 41, Issue s5, pp. S35-S39

DOI: 10.1111/j.1528-1157.2000.tb06047.x

Field-Weighted Citation Impact: 5.38

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Topiramate as an Inhibitor of Carbonic Anhydrase Isoenzymes

Authors

Abstract

Topics & Keywords

Publication Details