Trends in the postfortification prevalence of spina bifida and anencephaly in the United States

2008268 citationsJournal Articlegreen Open Access

Authors

Sheree L. Boulet · National Center on Birth Defects and Developmental Disabilities

Quanhe Yang · National Center on Birth Defects and Developmental Disabilities

Cara Mai · National Center on Birth Defects and Developmental Disabilities

Russell S. Kirby · University of Alabama at Birmingham

Julianne S. Collins · Greenwood Genetic Center

James M. Robbins · University of Arkansas for Medical Sciences

Abstract

While the prevalences of spina bifida and anencephaly in the United States have declined since folic acid fortification in the food supply began, these data suggest that reductions in the prevalence of anencephaly continued during 2001-2004 and that racial and ethnic and other disparities remain.

Topics & Keywords

Folate and B Vitamins Research Prenatal Screening and Diagnostics Congenital Anomalies and Fetal Surgery

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: Birth Defects Research Part A Clinical and Molecular Teratology

Volume 82, Issue 7, pp. 527-532

DOI: 10.1002/bdra.20468

Field-Weighted Citation Impact: 6.64