Drug Delivery with PEGylated MoS<sub>2</sub> Nano‐sheets for Combined Photothermal and Chemotherapy of Cancer

20141,202 citationsJournal Article

Authors

Teng Liu · Soochow University

Chao Wang · Soochow University

Xing Gu · Soochow University

Hua Gong · Soochow University

Liang Cheng · Soochow University

Xiaoze Shi · Soochow University

Liangzhu Feng · Soochow University

Abstract

MoS2 nanosheets functionalized with poly-ethylene glycol are for the first time used as a multifunctional drug delivery system with high drug loading capacities. Using doxorubicin as the model drug and taking advantages of the strong near-infrared absorbance of MoS2, combined photothermal and chemotherapy of cancer is realized in animal experiments, achieving excellent synergistic anti-tumor effect upon systemic administration.

Topics & Keywords

2D Materials and Applications Nanoplatforms for cancer theranostics MXene and MAX Phase Materials

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Advanced Materials

Volume 26, Issue 21, pp. 3433-3440

DOI: 10.1002/adma.201305256

Field-Weighted Citation Impact: 47.36