Association between the Interleukin-6 Promoter Polymorphism −174G/C and Serum Lipoprotein(a) Concentrations in Humans

201143 citationsJournal Articlegold Open Access

Authors

Heiner K. Berthold · Charité - Universitätsmedizin Berlin

Ioanna Gouni‐Berthold · University of Cologne

Abstract

The IL-6 single nucleotide polymorphism -174G/C is associated with increased odds of having elevated Lp(a). Whether this association plays a role in the Lp(a)-lowering effects of IL-6 receptor antagonists remains to be established.

Topics & Keywords

Adipokines, Inflammation, and Metabolic Diseases Atherosclerosis and Cardiovascular Diseases Lipoproteins and Cardiovascular Health

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS ONE

Volume 6, Issue 9, pp. e24719-e24719

DOI: 10.1371/journal.pone.0024719

Field-Weighted Citation Impact: 2.74