Pregnancy-Associated Plasma Protein A as a Marker of Acute Coronary Syndromes

2001559 citationsJournal Articlebronze Open Access

Authors

Antoni Bayés‐Genís · Mayo Clinic

Cheryl A. Conover

Michael T. Overgaard · Aarhus University

Kent R. Bailey

Michael Christiansen · Statens Serum Institut

David R. Holmes

Renu Virmani · Armed Forces Institute of Pathology

Claus Oxvig · Aarhus University

Abstract

PAPP-A is present in unstable plaques, and circulating levels are elevated in acute coronary syndromes; these increased levels may reflect the instability of atherosclerotic plaques. PAPP-A is a new candidate marker of unstable angina and acute myocardial infarction.

Topics & Keywords

Acute Myocardial Infarction Research Cardiovascular Effects of Exercise

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 345, Issue 14, pp. 1022-1029

DOI: 10.1056/nejmoa003147

Field-Weighted Citation Impact: 19.12