Induction of CD4+CD25+Foxp3+IL-10+ T Cells in HDM-Allergic Asthmatic Children with or without SIT

201031 citationsJournal Article

Authors

Wei Wang · Capital Medical University

Yongge Liu · Beijing Children’s Hospital

Yonghong Wang · Capital Medical University

Yuhong Zhao · Capital Medical University

Jianxin He · Capital Medical University

Li Xiang · Capital Medical University

Kunling Shen

Abstract

There is a functional, but quantitative, insufficiency of Treg cells in allergic asthmatic children, which was reversed in SIT-treated children. SIT can up-regulate the function of CD4(+)CD25(+)Foxp3(+) Treg cells.

Topics & Keywords

Allergic Rhinitis and Sensitization Asthma and respiratory diseases Dermatology and Skin Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: International Archives of Allergy and Immunology

Volume 153, Issue 1, pp. 19-26

DOI: 10.1159/000301575

Field-Weighted Citation Impact: 2.30

Command Palette

Induction of CD4&lt;sup&gt;+&lt;/sup&gt;CD25&lt;sup&gt;+&lt;/sup&gt;Foxp3&lt;sup&gt;+&lt;/sup&gt;IL-10&lt;sup&gt;+&lt;/sup&gt; T Cells in HDM-Allergic Asthmatic Children with or without SIT

Authors

Abstract

Topics & Keywords

UN Sustainable Development Goals

Publication Details

Induction of CD4<sup>+</sup>CD25<sup>+</sup>Foxp3<sup>+</sup>IL-10<sup>+</sup> T Cells in HDM-Allergic Asthmatic Children with or without SIT