Effect of an Intrauterine Device on the Gene Expression Profile of the Endometrium

200670 citationsJournal Article

Authors

J.A. Horcajadas · Universitat de València

Andrew Sharkey · University of Cambridge

Rob D. Catalano · University of Cambridge

J. R. A. Sherwin · University of Cambridge

Francisco Domı́nguez · Universitat de València

L. Burgos · Instituto Médico La Floresta

Ana Karolline Rocha de Castro ·

Abstract

Our results reveal that a refractory endometrium in a fertile woman produced by an IUD is induced by preventing the normal transition to a receptive gene expression profile through effects on a specific subset or cluster of genes that impact on endometrial receptivity.

Topics & Keywords

Reproductive System and Pregnancy Endometriosis Research and Treatment Ovarian function and disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Clinical Endocrinology & Metabolism

Volume 91, Issue 8, pp. 3199-3207

DOI: 10.1210/jc.2006-0430

Field-Weighted Citation Impact: 1.91