A Phase III Equivalence Trial of Azithromycin versus Benzathine Penicillin for Treatment of Early Syphilis

2010121 citationsJournal Articlebronze Open Access

Authors

Edward W. Hook · Jefferson County Department of Health

Frieda Behets · University of North Carolina at Chapel Hill

Kathleen Van Damme · University of North Carolina at Chapel Hill

Noro Lantoniaina Rosa Ravelomanana · Catholic University of Madagascar

Peter A. Leone · University of North Carolina at Chapel Hill

Arlene C. Seña · University of North Carolina at Chapel Hill

David H. Martin

Abstract

In this trial, the efficacy of azithromycin at a dosage of 2.0 g administered orally was equivalent to that of benzathine penicillin G for the treatment of early syphilis in persons without HIV infection.

Topics & Keywords

Syphilis Diagnosis and Treatment Reproductive tract infections research HIV/AIDS Research and Interventions

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Infectious Diseases

Volume 201, Issue 11, pp. 1729-1735

DOI: 10.1086/652239

Field-Weighted Citation Impact: 7.35