Sexually Transmitted Infection as a Cause of Anal Cancer

1997694 citationsJournal Articlebronze Open Access

Authors

Morten Frisch · Statens Serum Institut

Bengt Glimelius · Uppsala University Hospital

Adriaan J. C. van den Brule · Vrije Universiteit Amsterdam

Jan Wohlfahrt · Statens Serum Institut

Chris J.L.M. Meijer · Vrije Universiteit Amsterdam

Jan M.M. Walboomers · Vrije Universiteit Amsterdam

Sven Goldman

Abstract

Our study provides strong evidence that a sexually transmitted infection causes anal cancer. The presence of high-risk types of HPV, notably HPV-16 (which is known to cause cancer of the cervix), in the majority of anal-cancer tissue specimens suggests that most anal cancers are potentially preventable.

Topics & Keywords

Colorectal and Anal Carcinomas Cervical Cancer and HPV Research Viral-associated cancers and disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 337, Issue 19, pp. 1350-1358

DOI: 10.1056/nejm199711063371904

Field-Weighted Citation Impact: 16.26