Markers of angiogenesis (CD31, CD34, rCBV) and their prognostic value in low-grade gliomas

201338 citationsJournal Article

Authors

Krzysztof Majchrzak · Górnośląskie Centrum Medyczne

Wojciech Kaspera · Górnośląskie Centrum Medyczne

Janusz Szymaś · Poznan University of Medical Sciences

Barbara Bobek‐Billewicz · Centrum Onkologii

Anna Hebda · Centrum Onkologii

H Majchrzak · Górnośląskie Centrum Medyczne

Abstract

Density of microvessels as assessed immunohistochemically with CD31+ and CD34+ in LGG correlated with the value of rCBV in the tumour. The value of 1.75 for rCBV may be the threshold for better or poorer outcome of these patients. Expression of CD31 antigen is an important prognostic factor for the time of survival for patients with LGG.

Topics & Keywords

Glioma Diagnosis and Treatment Cell Adhesion Molecules Research Angiogenesis and VEGF in Cancer

UN Sustainable Development Goals

No poverty

Publication Details

Published in: Neurologia i Neurochirurgia Polska

Volume 47, Issue 4, pp. 325-331

DOI: 10.5114/ninp.2013.36757

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