Effects of Monobutyl and Di( n -butyl) Phthalate in Vitro on Steroidogenesis and Leydig Cell Aggregation in Fetal Testis Explants from the Rat: Comparison with Effects in Vivo in the Fetal Rat and Neonatal Marmoset and in Vitro in the Human

2006183 citationsJournal Articlediamond Open Access

Authors

Nina Hallmark · MRC Centre for Reproductive Health

Marion Walker · MRC Centre for Reproductive Health

Chris McKinnell · MRC Centre for Reproductive Health

I. Kim Mahood · MRC Centre for Reproductive Health

Hayley M. Scott · MRC Centre for Reproductive Health

Rosemary A. L. Bayne · MRC Centre for Reproductive Health

Shiona M. Coutts

Abstract

These findings suggest that MBP/DBP suppresses steroidogenesis by fetal-type Leydig cells in primates as in rodents, but this cannot be studied in vitro.

Topics & Keywords

Effects and risks of endocrine disrupting chemicals Sexual Differentiation and Disorders Sperm and Testicular Function

Publication Details

Published in: Environmental Health Perspectives

Volume 115, Issue 3, pp. 390-396

DOI: 10.1289/ehp.9490

Field-Weighted Citation Impact: 6.39

Command Palette

Effects of Monobutyl and Di( <i>n</i> -butyl) Phthalate <i>in Vitro</i> on Steroidogenesis and Leydig Cell Aggregation in Fetal Testis Explants from the Rat: Comparison with Effects <i>in Vivo</i> in the Fetal Rat and Neonatal Marmoset and <i>in Vitro</i> in the Human

Authors

Abstract

Topics & Keywords

Publication Details