The Preclinical Alzheimer Cognitive Composite

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Authors

Michael Donohue · Alzheimer’s Disease Neuroimaging Initiative

Reisa A. Sperling · Harvard University

David P. Salmon · Alzheimer’s Disease Neuroimaging Initiative

Dorene M. Rentz · Harvard University

Rema Raman · Alzheimer’s Disease Neuroimaging Initiative

Ronald G. Thomas · Alzheimer’s Disease Neuroimaging Initiative

Michael Weiner

Abstract

Analyses of at-risk cognitively normal populations suggest that we can reliably measure the first signs of cognitive decline with the ADCS-PACC. These analyses also suggest the feasibility of secondary prevention trials.

Topics & Keywords

Dementia and Cognitive Impairment Research Alzheimer's disease research and treatments Functional Brain Connectivity Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA Neurology

Volume 71, Issue 8, pp. 961-961

DOI: 10.1001/jamaneurol.2014.803

Field-Weighted Citation Impact: 24.39