Association Between the Various Mutations in Viral Core Promoter Region to Different Stages of Hepatitis B, Ranging of Asymptomatic Carrier State to Hepatocellular Carcinoma

2010150 citationsJournal Article

Authors

Jianhua Yin · Second Military Medical University

Jiaxin Xie · Second Military Medical University

Shijian Liu · Second Military Medical University

Hongwei Zhang · Second Military Medical University

Lei Han · Second Military Medical University

Wenying Lu · Second Military Medical University

Qiuxia Shen

Abstract

C1673T, A1726C, A1727T, C1730G, C1766T, T1768A, C1773T, and C1799G in genotype C are specific for cirrhosis. A1846T and T1674C/G are novel factors independently associated with cirrhosis and HCC, respectively.

Topics & Keywords

Hepatitis B Virus Studies Liver Disease Diagnosis and Treatment Hepatitis C virus research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The American Journal of Gastroenterology

Volume 106, Issue 1, pp. 81-92

DOI: 10.1038/ajg.2010.399

Field-Weighted Citation Impact: 7.02