The Clinical Utilization of Circulating Cell Free DNA (CCFDNA) in Blood of Cancer Patients

2013236 citationsReviewgold Open Access

Authors

Yahya Elshimali · Charles R. Drew University of Medicine and Science

Marianna Sarkissyan · Charles R. Drew University of Medicine and Science

Yanyuan Wu · UCLA Jonsson Comprehensive Cancer Center

Jaydutt Vadgama · Charles R. Drew University of Medicine and Science

Abstract

Qualitative and quantitative testing of circulating cell free DNA (CCFDNA) can be applied for the management of malignant and benign neoplasms. Detecting circulating DNA in cancer patients may help develop a DNA profile for early stage diagnosis in malignancies. The technical issues of obtaining, using, and analyzing CCFDNA from blood will be discussed.

Topics & Keywords

Cancer Genomics and Diagnostics Genetic factors in colorectal cancer Renal cell carcinoma treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: International Journal of Molecular Sciences

Volume 14, Issue 9, pp. 18925-18958

DOI: 10.3390/ijms140918925

Field-Weighted Citation Impact: 7.21