Iodine–PPh3-mediated C3-sulfenylation of indoles with sodium sulfinates

201480 citationsJournal Article

Authors

Praewpan Katrun · Mahidol University

Sakchai Hongthong · Mahidol University

Sornsiri Hlekhlai · Mahidol University

Manat Pohmakotr · Mahidol University

Vichai Reutrakul · Mahidol University

Darunee Soorukram · Mahidol University

Thaworn Jaipetch ·

Abstract

3-(Alkylsulfanyl)- and 3-(arylsulfanyl)indoles were efficiently prepared by the reaction of indoles with sodium sulfinates mediated by iodine–PPh3 in ethanol. The salient features of the present protocol are simplicity, high efficiency, non-anhydrous conditions, environmentally friendly reagents and solvent, and short reaction time.

Topics & Keywords

Sulfur-Based Synthesis Techniques Chemical Synthesis and Reactions Catalytic C–H Functionalization Methods

UN Sustainable Development Goals

Responsible consumption and production

Publication Details

Published in: RSC Advances

Volume 4, Issue 36, pp. 18933-18933

DOI: 10.1039/c4ra02607a

Field-Weighted Citation Impact: 5.89