Generalized Gastrointestinal Polyposis

TWO cases are reported below in which the presenting complaints were disturbances in gastrointestinal function, pigmentation of the skin, alopecia and atrophy of the fingernails and toenails. In each case the underlying pathologic process seemed to be generalized gastrointestinal polyposis in which virtually the entire gastrointestinal mucosa was replaced by polypoid lesions. These cases are of interest in that they probably differ in nature from other syndromes that relate polyposis to pigmentation of the skin.Case ReportsCASE 1. E.S. (B.M. 733228), a 42-year-old single female bookkeeper, was first seen in March, 1951, because of nausea, vomiting and diarrhea of . . .