Long-term Vision Rescue by Human Neural Progenitors in a Rat Model of Photoreceptor Degeneration

2008116 citationsJournal Articlegreen Open Access

Authors

Shaomei Wang · Oregon Health & Science University

Sergej Girman · Oregon Health & Science University

Bin Lü · Oregon Health & Science University

Nicholas Bischoff · Eye Institute of Utah

Toby Holmes · University College Dublin

R. Shearer · Pisgah Astronomical Research Institute

Lynda S. Wright

Abstract

Long-term rescue of function and associated morphologic substrates was seen, together with donor cell survival even in the xenograft paradigm. This is encouraging when exploring further the potential for the application of hNPC(ctx) in treating retinal disease.

Topics & Keywords

Retinal Development and Disorders Retinal Diseases and Treatments Retinal and Macular Surgery

UN Sustainable Development Goals

Life in Land

Publication Details

Published in: Investigative Ophthalmology & Visual Science

Volume 49, Issue 7, pp. 3201-3201

DOI: 10.1167/iovs.08-1831

Field-Weighted Citation Impact: 3.77