Endoplasmic reticulum stress induces autophagy in renal proximal tubular cells

2009104 citationsJournal Articlebronze Open Access

Authors

Toshiaki Kawakami · The University of Tokyo

Reiko Inagi · The University of Tokyo

Hideki Takano · The University of Tokyo

Shuzo Sato · Nippon Medical School

Julie R. Ingelfinger · Harvard University

Toshiro Fujita · The University of Tokyo

Masaomi Nangaku ·

Abstract

For the first time, we demonstrate the induction of autophagy following ER stress in renal tubules, and clarify its mechanism. These findings serve as the foundation for further investigation into autophagy in renal diseases.

Topics & Keywords

Autophagy in Disease and Therapy Cannabis and Cannabinoid Research Endoplasmic Reticulum Stress and Disease

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Nephrology Dialysis Transplantation

Volume 24, Issue 9, pp. 2665-2672

DOI: 10.1093/ndt/gfp215

Field-Weighted Citation Impact: 5.98