The GPI Anchor Signal Sequence Dictates the Folding and Functionality of the Als5 Adhesin from Candida albicans

201217 citationsJournal Articlegold Open Access

Authors

Mohammad Faiz Ahmad · Jamia Millia Islamia

Bhawna Yadav · Jawaharlal Nehru University

Pravin Kumar · University of Delhi

Amrita Puri · Invisible Software (United States)

Mohit Mazumder · Jawaharlal Nehru University

Anwar Ali · Jamia Millia Islamia

Samudrala Gourinath ·

Abstract

We propose that the locking of the conformation of the precursor protein in an alternate conformation from that of the mature protein is one probable strategy employed by the cell to control the behaviour and function of proteins intended to be GPI anchored during their transit through the ER.

Topics & Keywords

Carbohydrate Chemistry and Synthesis Biochemical and Structural Characterization Glycosylation and Glycoproteins Research

Publication Details

Published in: PLoS ONE

Volume 7, Issue 4, pp. e35305-e35305

DOI: 10.1371/journal.pone.0035305

Field-Weighted Citation Impact: 0.62

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The GPI Anchor Signal Sequence Dictates the Folding and Functionality of the Als5 Adhesin from Candida albicans

Authors

Abstract

Topics & Keywords

Publication Details