A randomized placebo-controlled study on the effect of nifedipine on coronary endothelial function and plaque formation in patients with coronary artery disease: the ENCORE II study

200993 citationsJournal Articlehybrid Open Access

Authors

Thomas F. Lüscher · University of Zurich

Micheal Pieper

Michał Tendera · Górnośląska Wyższa Szkoła Handlowa im. Wojciecha Korfantego

Matty Vrolix

Wolfgang Rutsch · Humboldt-Universität zu Berlin

F. Van Den Branden · ZNA Middelheim Hospital

Robert Gil

K Bischoff · Krankenhaus Waldfriede

Abstract

The ENCORE II trial demonstrates in a multi-centre setting that calcium channel blockade with nifedipine for up to 2 years improves coronary endothelial function on top of statin treatment, but did not show an effect of nifedipine on plaque volume.

Topics & Keywords

Blood Pressure and Hypertension Studies Antiplatelet Therapy and Cardiovascular Diseases Cardiac Imaging and Diagnostics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: European Heart Journal

Volume 30, Issue 13, pp. 1590-1597

DOI: 10.1093/eurheartj/ehp151

Field-Weighted Citation Impact: 6.31