One-step Nucleic Acid Amplification for Intraoperative Detection of Lymph Node Metastasis in Breast Cancer Patients

2007441 citationsJournal Article

Authors

Masahiko Tsujimoto · Osaka Police Hospital

Kadzuki Nakabayashi · Sysmex (Japan)

Katsuhide Yoshidome · Osaka Police Hospital

Tomoyo Kaneko

Takuji Iwase · Cancer Institute (WIA)

Abstract

The OSNA assay of half of a lymph node provided results similar to those of three-level histopathology. Clinical results indicate that the OSNA assay provides a useful intraoperative detection method of lymph node metastasis in breast cancer patients.

Topics & Keywords

Molecular Biology Techniques and Applications Advanced biosensing and bioanalysis techniques Breast Cancer Treatment Studies

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: Clinical Cancer Research

Volume 13, Issue 16, pp. 4807-4816

DOI: 10.1158/1078-0432.ccr-06-2512

Field-Weighted Citation Impact: 6.16