Thiazolidinediones, Metformin, and Outcomes in Older Patients With Diabetes and Heart Failure

2005458 citationsJournal Articlebronze Open Access

Authors

Frederick A. Masoudi · Denver Health Medical Center

Silvio E. Inzucchi · University of Colorado Denver

Yongfei Wang · Arkansas Foundation for Medical Care

Edward P. Havranek · University of Colorado Health

JoAnne M. Foody · Denver Health Medical Center

Harlan M. Krumholz · Denver Health Medical Center

Abstract

This observational study suggests that thiazolidinediones and metformin are not associated with increased mortality and may improve outcomes in older patients with diabetes and heart failure. Randomized trials are warranted to corroborate these findings.

Topics & Keywords

Diabetes Treatment and Management Cardiovascular Function and Risk Factors Heart Failure Treatment and Management

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 111, Issue 5, pp. 583-590

DOI: 10.1161/01.cir.0000154542.13412.b1

Field-Weighted Citation Impact: 19.08