High Concentrations of Pamidronate in Bone Weaken the Mechanical Properties of Intact Femora in a Rat Model

200724 citationsJournal Articlegold Open Access

Authors

Kyu Hyun Yang · Yonsei University

Jung Hoon Won · Yonsei University

Han Kook Yoon · Yonsei University

Jong Hyeon Ryu · Hanlim Pharm (South Korea)

Kyo Seok Choo · Hanlim Pharm (South Korea)

Jae Shin Kim · Hanlim Pharm (South Korea)

Abstract

High concentrations of pamidronate in intact bone decreased the bone mineral density and weakened the mechanical strength of the rat femora. The mechanical strength of the early healing callus was not correlated with concentration of pamidronate in the bone.

Topics & Keywords

Bone health and treatments Bone health and osteoporosis research Bone and Joint Diseases

Publication Details

Published in: Yonsei Medical Journal

Volume 48, Issue 4, pp. 653-653

DOI: 10.3349/ymj.2007.48.4.653

Field-Weighted Citation Impact: 1.35

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High Concentrations of Pamidronate in Bone Weaken the Mechanical Properties of Intact Femora in a Rat Model

Authors

Abstract

Topics & Keywords

Publication Details