Effects of 23.4% Sodium Chloride Solution in Reducing Intracranial Pressure in Patients with Traumatic Brain Injury: A Preliminary Study

2005144 citationsJournal Article

Authors

Marcus Ware · University of Illinois Chicago

Venu M. Nemani · Neurological Surgery

Michele Meeker · Neurological Surgery

Currie Lee · University of California, San Francisco

Diane Morabito · Neurological Surgery

Geoffrey T. Manley · Neurological Surgery

Abstract

This study suggests that 23.4% hypertonic saline is a safe and effective treatment for elevated ICP in patients after traumatic brain injury. These results warrant a rigorous evaluation of its efficacy as compared to mannitol in a prospective randomized controlled trial.

Topics & Keywords

Traumatic Brain Injury and Neurovascular Disturbances Anesthesia and Neurotoxicity Research Cardiac Arrest and Resuscitation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neurosurgery

Volume 57, Issue 4, pp. 727-736

DOI: 10.1227/01.neu.0000175726.08903.0a

Field-Weighted Citation Impact: 5.43