A multicenter, randomized, double‐blind, placebo‐controlled trial of adjuvant methotrexate treatment for giant cell arteritis

2002570 citationsJournal Article

Authors

Gary S. Hoffman · Cleveland Clinic

María C. Cid · Hospital Clínic de Barcelona

David B. Hellmann · Johns Hopkins University

Loı̈c Guillevin · Université Paris 8

John H. Stone · Johns Hopkins University

John T. Schousboe

Pascal Cohen · Université Sorbonne Paris Nord

Abstract

The results of this randomized, multicenter trial do not support the adjunctive use of MTX to control disease activity or to decrease the cumulative dose and toxicity of CS in patients with GCA.

Topics & Keywords

Vasculitis and related conditions Otitis Media and Relapsing Polychondritis Coagulation, Bradykinin, Polyphosphates, and Angioedema

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Arthritis & Rheumatism

Volume 46, Issue 5, pp. 1309-1318

DOI: 10.1002/art.10262

Field-Weighted Citation Impact: 13.68