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Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

20092,068 citationsJournal Article

Authors

Shih-Min A. Huang · Novartis (Switzerland)

Yuji Mishina · Novartis (Switzerland)

Shanming Liu · Novartis (Switzerland)

Atwood K. Cheung · Novartis (Switzerland)

Frank Stegmeier · Novartis (Switzerland)

Gregory A. Michaud · Novartis (Switzerland)

Olga Charlat ·

Topics & Keywords

Wnt/β-catenin signaling in development and cancer Cancer-related gene regulation Polyamine Metabolism and Applications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Nature

Volume 461, Issue 7264, pp. 614-620

DOI: 10.1038/nature08356

Field-Weighted Citation Impact: 37.92

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling | Researchclopedia

Novartis (Switzerland)

Elizabeth L. Wiellette · Novartis (Switzerland)

Yue Zhang · Novartis (Switzerland)

Stephanie Wiessner · Novartis (Switzerland)

Marc Hild · Novartis (Switzerland)

Xiaoying Shi · Novartis (Switzerland)

Christopher J. Wilson · Novartis (Switzerland)

Craig Mickanin · Novartis (Switzerland)

Vic E. Myer · Novartis (Switzerland)

Aleem Fazal · Novartis (Switzerland)

Ronald Tomlinson · Novartis (Switzerland)

Fabrizio C. Serluca · Novartis (Switzerland)

Wenlin Shao · Novartis (Switzerland)

Hong Cheng · Novartis (Switzerland)

Michael D. Shultz · Novartis (Switzerland)

Markus Schirle · Novartis Foundation

Stephen E. Fawell · Novartis (Switzerland)

Chuang Lu · Novartis (Switzerland)

Daniel Curtis · Novartis (Switzerland)

Marc W. Kirschner · Harvard University

Christoph Lengauer · Novartis Foundation

Peter M. Finan · Novartis (Switzerland)

John A. Tallarico · Novartis (Switzerland)

Tewis Bouwmeester · Novartis Foundation

Jeffery A. Porter · Novartis (Switzerland)

Andreas Bauer · Novartis Foundation

Feng Cong · Novartis (Switzerland)