Comparative Analysis of African Swine Fever Virus Genotypes and Serogroups

2015169 citationsJournal Articlediamond Open Access

Authors

Alexander Malogolovkin · National Research Institute for Veterinary Virology and Microbiology of Russia

Galina Koltsova · National Research Institute for Veterinary Virology and Microbiology of Russia

Ilya Titov · National Research Institute for Veterinary Virology and Microbiology of Russia

Alexey D. Sereda · National Research Institute for Veterinary Virology and Microbiology of Russia

Gogin Andrey · National Research Institute for Veterinary Virology and Microbiology of Russia

Elena Baryshnikova · National Research Institute for Veterinary Virology and Microbiology of Russia

Abstract

African swine fever virus (ASFV) causes highly lethal hemorrhagic disease among pigs, and ASFV's extreme antigenic diversity hinders vaccine development. We show that p72 ASFV phylogenetic analysis does not accurately define ASFV hemadsorption inhibition assay serogroups. Thus, conventional ASFV genotyping cannot discriminate between viruses of different virulence or predict efficacy of a specific ASFV vaccine.

Topics & Keywords

Animal Disease Management and Epidemiology Vector-Borne Animal Diseases Viral gastroenteritis research and epidemiology

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: Emerging infectious diseases

Volume 21, Issue 2, pp. 312-315

DOI: 10.3201/eid2102.140649

Field-Weighted Citation Impact: 14.48