Troglitazone Reduces Plasma Leptin Concentration but Increases Hunger in NIDDM Patients

1998116 citationsJournal Article

Authors

Hiroyuki Shimizu · Gunma University

Takahumi Tsuchiya · Gunma University

Noriyuki Sato · Gunma University

Yohnosuke Shimomura · Gunma Prefectural College of Health Sciences

Isao Kobayashi · Gunma University

Masatomo Mori · Gunma University

Abstract

Troglitazone significantly reduces circulating leptin levels at clinical doses. It may affect the eating behavior of poorly controlled NIDDM patients through the improvement of glycemic control and/or the reduction of circulating leptin.

Topics & Keywords

Regulation of Appetite and Obesity Adipose Tissue and Metabolism Adipokines, Inflammation, and Metabolic Diseases

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: Diabetes Care

Volume 21, Issue 9, pp. 1470-1474

DOI: 10.2337/diacare.21.9.1470

Field-Weighted Citation Impact: 2.47