Characterization and Functionality of Cardiac Progenitor Cells in Congenital Heart Patients

2011214 citationsJournal Articlebronze Open Access

Authors

Rachana Mishra · University of Nevada, Reno

Kalpana Vijayan · University of Nevada, Reno

Evan Colletti · University of Nevada, Reno

Daniel A. Harrington · Northwestern University

T Matthiesen · Northwestern University

David Simpson · University of Illinois Chicago

Saik Kia Goh ·

Abstract

Resident hCPCs are most abundant in the neonatal period and rapidly decrease over time. hCDCs can be reproducibly isolated and expanded from young human myocardial samples regardless of age or diagnosis. hCPCs are functional and have potential in congenital cardiac repair.

Topics & Keywords

Congenital heart defects research Tissue Engineering and Regenerative Medicine Cardiac Structural Anomalies and Repair

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 123, Issue 4, pp. 364-373

DOI: 10.1161/circulationaha.110.971622

Field-Weighted Citation Impact: 10.29