Sexually dimorphic expression of Dax‐1 in the adrenal cortex

200254 citationsJournal Article

Authors

Tokuo Mukai · National Institute for Basic Biology

Masatomo Kusaka · The Graduate University for Advanced Studies, SOKENDAI

Ken Kawabe · Kyushu University

Kiminobu Goto · Japan Science and Technology Agency

Hajime Nawata · Japan Science and Technology Agency

Kenji Fujieda · Asahikawa Medical College Hospital

Ken‐ichirou Morohashi

Abstract

The present study revealed that the expression of Dax-1 in the adrenal cortex is regulated by androgen and the receptor. Interestingly, AR acts as a suppressor in the presence of the ligand through interaction with Ad4BP/SF-1.

Topics & Keywords

Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities Estrogen and related hormone effects Sexual Differentiation and Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Genes to Cells

Volume 7, Issue 7, pp. 717-729

DOI: 10.1046/j.1365-2443.2002.00556.x

Field-Weighted Citation Impact: 1.89